I know this idea is somewhat of a copy of the Ipod Touch idea..but my idea is a life size version Blackberry Curve.
I was thinking about putting a ~20" monitor for the screen like this one: http://www.newegg.com/Product/Product.aspx?Item=N82E16824009158. For the mouse, just take like a trackball mouse such as http://www.newegg.com/Product/Product.aspx?Item=N82E16826125019. And could make the send the power button and the end call the shutdown button. For the keyboard im not sure how you'd do that..and for the speaker up top you could just put some sort of a slim speaker. I think the ION Platform is sort of like a blackberry, a small handheld PC.